Search results for " Human Platelet"

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PLA1/A2 polymorphism of the platelet glycoprotein receptors IIIA in Behçet's disease

2010

OBJECTIVES: To investigate potential associations between the PlA1/A2 polymorphism of the platelet glycoprotein receptor IIIA (GpIIIa) gene and venous thrombosis and other clinical manifestations in Italian patients with Behçet's disease (BD). METHODS: Two hundred consecutive Italian patients satisfying the International Study Group criteria for BD who were followed up for seven years and 241 healthy Italian age- and gender-matched blood donors were molecularly genotyped for the PlA1/A2 polymorphism of the platelet GpIIIa gene; 118 and 117 of the 200 BD patients were also respectively genotyped for factor V Leiden and prothrombin gene G20210A polymorphisms. A standard microlymphocytotoxicit…

AdultBlood PlateletsMaleVenous ThrombosisPolymorphism GeneticAdolescentGenotypeBehcet SyndromeIntegrin beta3Factor VPLA1/2 polymorphism Behcet's diseaseYoung AdultHuman PlateletGene FrequencyGeneticHumansAntigens Human PlateletFemaleProthrombinAdolescent; Adult; Antigens Human Platelet; Blood Platelets; Factor V; Female; Gene Frequency; Genotype; Humans; Integrin beta3; Male; Polymorphism Genetic; Prothrombin; Young Adult; Behcet Syndrome; Venous ThrombosisAntigensPolymorphism

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